We are currently seeking a candidate for a postdoctoral position in colorectal cancer (CRC) research. The project will explore the role of goblet cell-intrinsic mucosal defence systems in determining susceptibility to CRC.The candidate will join a newly established Wallenberg Centre for Molecular and Translational Medicine (WCMTM) at the University of Gothenburg (https://wcmtm.gu.se/). As part of this venture, Dr. George Birchenough has established his research group (https://www.birchenoughlab.org/) at the Department of Medical Biochemistry & Cell Biology at the University of Gothenburg. The group works towards a better understanding of how mucosal defence systems control our interactions with the environment, how those systems fail in disease and how they might be prophylactically or therapeutically targeted.The group is part of a large network of researchers at Gothenburg University, most importantly the Mucin Biology Groups cluster (http://www.medkem.gu.se/mucinbiology/) that currently includes over 30 researchers working at the forefront of mucosal biology. The candidate will have the opportunity to collaborate with experts in multiple experimental methods that work within the cluster, as well as more widely with other local and national groups within the WCMTM network.Subject area Translational Mucosal BiologySubject area description Our mucosal surfaces are the interface between the environment and our tissues. Their physiological functions are critical, but necessitate constant exposure of living cells to a vast collection of microbial lifeforms that includes many opportunistic and obligate pathogens. As a result, our mucosa has evolved multiple defensive systems that allow them to endure in this environment, and failure of these systems is often l…MolekylärbiologCell- och molekylärbiologer m.fl.
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